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Polypyrimidine Tract-Binding Protein MeSH Descriptor Data 2025


MeSH Heading
Polypyrimidine Tract-Binding Protein
Tree Number(s)
D12.776.157.725.829.250
D12.776.664.962.829.250
Unique ID
D038941
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D038941
Scope Note
A RNA-binding protein that binds to polypyriminidine rich regions in the INTRONS of messenger RNAs. Polypyrimidine tract-binding protein may be involved in regulating the ALTERNATIVE SPLICING of mRNAs since its presence on an intronic RNA region that is upstream of an EXON inhibits the splicing of the exon into the final mRNA product.
Entry Term(s)
PTB Protein
PTB Splicing Factor
p57 Cytoplasmic RNA-Binding Protein
pPTB
Registry Numbers
139076-35-0
Previous Indexing
Ribonucleoproteins (1991-2002)
RNA-Binding Proteins (1991-2002)
Public MeSH Note
2003; POLYPYRIMIDINE TRACT-BINDING PROTEIN was indexed under RIBONUCLEOPROTEINS & RNA-BINDING PROTEINS 1991-2002
History Note
2003; use POLYPYRIMIDINE TRACT-BINDING PROTEIN (NM) 1991-2002
Date Established
2003/01/01
Date of Entry
2002/07/03
Revision Date
2016/07/05
Polypyrimidine Tract-Binding Protein Preferred
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