MeSH Browser

MeSH Heading: Ribonucleoprotein, U2 Small Nuclear
Tree Number(s): D12.776.157.725.500.875.605; D12.776.157.725.829.344; D12.776.664.962.500.875.605; D12.776.664.962.829.344
Unique ID: D017413
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D017413
Scope Note: A nuclear RNA-protein complex that plays a role in RNA processing. In the nucleoplasm, the U2 snRNP along with other small nuclear ribonucleoproteins (U1, U4-U6, and U5) assemble into SPLICEOSOMES that remove introns from pre-mRNA by splicing. The U2 snRNA forms base pairs with conserved sequence motifs at the branch point, which associates with a heat- and RNAase-sensitive factor in an early step of splicing.
Entry Term(s): Ribonucleoproteins, Small, U2; Small Nuclear Ribonucleoproteins, U2; U2 Small Nuclear Ribonucleoproteins; U2 snRNP
Previous Indexing: Ribonucleoproteins (1975-1992)
Public MeSH Note: 2000; RIBONUCLEOPROTEINS, SMALL, U2 was heading 1993-1999; SNRNP-U2 was indexed under RIBONUCLEOPROTEINS 1982-92
History Note: 2000; U2 SNRNP was SNRNP-U2 (SY) to SMALL RIBONUCLEOPROTEINS (NM) 1982-92
Date Established: 1993/01/01
Date of Entry: 1992/05/22
Revision Date: 2016/07/05

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0026430
Scope Note: A nuclear RNA-protein complex that plays a role in RNA processing. In the nucleoplasm, the U2 snRNP along with other small nuclear ribonucleoproteins (U1, U4-U6, and U5) assemble into SPLICEOSOMES that remove introns from pre-mRNA by splicing. The U2 snRNA forms base pairs with conserved sequence motifs at the branch point, which associates with a heat- and RNAase-sensitive factor in an early step of splicing.
Terms: Ribonucleoprotein, U2 Small Nuclear Preferred Term
Term UI T365020
Date11/03/1999
LexicalTag NON
ThesaurusID NLM (2000); Small Nuclear Ribonucleoproteins, U2
Term UI T052081
Date03/25/1992
LexicalTag NON
ThesaurusID NLM (1993); U2 Small Nuclear Ribonucleoproteins
Term UI T052082
Date03/25/1992
LexicalTag NON
ThesaurusID NLM (1993); U2 snRNP
Term UI T052083
Date03/25/1992
LexicalTag ABB
ThesaurusID NLM (1993); Ribonucleoproteins, Small, U2
Term UI T052084
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1993)

Ribonucleoprotein, U2 Small Nuclear MeSH Descriptor Data 2024