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Ribonucleoprotein, U1 Small Nuclear MeSH Descriptor Data 2023


MeSH Heading
Ribonucleoprotein, U1 Small Nuclear
Tree Number(s)
D12.776.157.725.500.875.600
D12.776.157.725.829.313
D12.776.664.962.500.875.600
D12.776.664.962.829.313
Unique ID
D017412
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D017412
Scope Note
A nuclear RNA-protein complex that plays a role in RNA processing. In the nucleoplasm, the U1 snRNP along with other small nuclear ribonucleoproteins (U2, U4-U6, and U5) assemble into SPLICEOSOMES that remove introns from pre-mRNA by splicing. The U1 snRNA forms base pairs with conserved sequence motifs at the 5'-splice site and recognizes both the 5'- and 3'-splice sites and may have a fundamental role in aligning the two sites for the splicing reaction.
Entry Term(s)
Ribonucleoproteins, Small, U1
Small Nuclear Ribonucleoproteins, U1
U1 Small Nuclear Ribonucleoproteins
U1 snRNP
Registry Number
0
Previous Indexing
Ribonucleoproteins (1975-1992)
Public MeSH Note
2000; RIBONUCLEOPROTEINS, SMALL, U1 was heading 1993-1999; U1-RNP was indexed under RIBONUCLEOPROTEINS 1982-92
History Note
2000; U1 SNRNP was U1-RNP (SY) to SMALL RIBONUCLEOPROTEINS (NM) 1982-92
Date Established
1993/01/01
Date of Entry
1992/05/22
Revision Date
2016/07/05
Ribonucleoprotein, U1 Small Nuclear Preferred
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