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tau Proteins MeSH Descriptor Data 2022


MeSH Heading
tau Proteins
Tree Number(s)
D12.776.220.600.450.510
D12.776.631.560.510
Unique ID
D016875
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D016875
Scope Note
Microtubule-associated proteins that are mainly expressed in neurons. Tau proteins constitute several isoforms and play an important role in the assembly of tubulin monomers into microtubules and in maintaining the cytoskeleton and axonal transport. Aggregation of specific sets of tau proteins in filamentous inclusions is the common feature of intraneuronal and glial fibrillar lesions (NEUROFIBRILLARY TANGLES; NEUROPIL THREADS) in numerous neurodegenerative disorders (ALZHEIMER DISEASE; TAUOPATHIES).
Entry Term(s)
tau Protein
Registry Number
0
Previous Indexing
Microtubule-Associated Proteins (1986-1991)
Microtubules (1976-1985)
See Also
Tauopathies
Public MeSH Note
1992; TAU (NM) was indexed under MICROTUBULE-ASSOCIATED PROTEINS 1985-91 & under PROTEINS 1977-84
Online Note
use TAU PROTEINS (NM) to search TAU (NM) 1980-90
History Note
1992; use TAU (NM) 1977-91
Date Established
1992/01/01
Date of Entry
1991/07/12
Revision Date
2016/07/05
tau Proteins Preferred
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