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Calcimycin MeSH Descriptor Data 2023


MeSH Heading
Calcimycin
Tree Number(s)
D03.633.100.221.173
Unique ID
D000001
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000001
Scope Note
An ionophorous, polyether antibiotic from Streptomyces chartreusensis. It binds and transports CALCIUM and other divalent cations across membranes and uncouples oxidative phosphorylation while inhibiting ATPase of rat liver mitochondria. The substance is used mostly as a biochemical tool to study the role of divalent cations in various biological systems.
Entry Term(s)
A-23187
A23187
Antibiotic A23187
Pharm Action
Anti-Bacterial Agents
Calcium Ionophores
Registry Number
37H9VM9WZL
Related Numbers
52665-69-7
CAS Type 1 Name
4-Benzoxazolecarboxylic acid, 5-(methylamino)-2-((3,9,11-trimethyl-8-(1-methyl-2-oxo-2-(1H-pyrrol-2-yl)ethyl)-1,7-dioxaspiro(5.5)undec-2-yl)methyl)-, (6S-(6alpha(2S*,3S*),8beta(R*),9beta,11alpha))-
Previous Indexing
Antibiotics (1973-1974)
Carboxylic Acids (1973-1974)
Public MeSH Note
91; was A 23187 1975-90 (see under ANTIBIOTICS 1975-83)
Online Note
use CALCIMYCIN to search A 23187 1975-90
History Note
91(75); was A 23187 1975-90 (see under ANTIBIOTICS 1975-83)
Date Established
1984/01/01
Date of Entry
1974/11/19
Revision Date
2016/05/27
Calcimycin Preferred
A-23187 Narrower
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