MeSH Browser

MeSH Heading: Duloxetine Hydrochloride
Tree Number(s): D02.886.778.260; D03.383.903.260
Unique ID: D000068736
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000068736
Scope Note: A thiophene derivative and selective NEUROTRANSMITTER UPTAKE INHIBITOR for SEROTONIN and NORADRENALINE (SNRI). It is an ANTIDEPRESSIVE AGENT and ANXIOLYTIC, and is also used for the treatment of pain in patients with DIABETES MELLITUS and FIBROMYALGIA.
Entry Term(s): Cymbalta; Duloxetine; Duloxetine Ethanedioate (1:1), (+-)-isomer - T353987; Duloxetine HCl; Duloxetine, (+)-isomer; LY 227942; LY 248686; LY-227942; LY-248686; LY227942; N-methyl-3-(1-naphthalenyloxy)-2-thiophenepropanamine; N-methyl-3-(1-naphthalenyloxy)-3-(2-thiophene)propanamide
Pharm Action: Analgesics
Antidepressive Agents
Dopamine Agents
Serotonin and Noradrenaline Reuptake Inhibitors
Registry Numbers: 9044SC542W; O5TNM5N07U; 0; 118625-29-9; 116539-59-4
Related Numbers: 116539-58-3; 116539-59-4; 116539-60-7; 118625-29-9; 136434-34-9; O5TNM5N07U
Public MeSH Note: 2016; DULOXETINE was indexed under THIOPHENES 1989-2015
History Note: 2016 (1989)
Date Established: 2016/01/01
Date of Entry: 2015/07/09
Revision Date: 2016/05/31

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Duloxetine Hydrochloride MeSH Descriptor Data 2025