MeSH Browser

MeSH Heading: Thioctic Acid
Tree Number(s): D02.241.803; D02.886.778.827; D08.211.906; D10.251.941
Unique ID: D008063
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D008063
Scope Note: An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.
Entry Term(s): Alpha-Lipogamma; Alpha-Lipon Stada; Alpha-Liponsaure Sofotec; Alpha-Lippon AL; Alphaflam; Azulipont; Fenint; Juthiac; Lipoic Acid; Liponsaure-ratiopharm; MTW-Alphaliponsaure; Neurium; Pleomix-Alpha; Pleomix-Alpha N; Thioctacid; Thioctacide T; Thiogamma Injekt; Thiogamma oral; Tromlipon; Verla-Lipon; alpha-Lipoic Acid; alpha-Liponaure Heumann; alpha-Liponsaure von ct; alpha-Vibolex; biomo-lipon; duralipon; espa-lipon
Pharm Action: Antioxidants
Vitamin B Complex
Registry Numbers: 73Y7P0K73Y; 0
Related Numbers: 62-46-4
CAS Type 1 Name: 1,2-Dithiolane-3-pentanoic acid
NLM Classification #: QU 135
Public MeSH Note: 91; was LIPOIC ACID 1963-90
Online Note: use THIOCTIC ACID to search LIPOIC ACID 1966-90
History Note: 91; was LIPOIC ACID 1963-90
Date Established: 1991/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/07/01

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0012565
Registry Numbers: 73Y7P0K73Y
Related Numbers: 62-46-4
Scope Note: An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.
Terms: Thioctic Acid Preferred Term
Term UI T024036
Date01/01/1999
LexicalTag NON
ThesaurusID; alpha-Lipoic Acid
Term UI T024034
Date11/18/1986
LexicalTag NON
ThesaurusID; Lipoic Acid
Term UI T024035
Date02/28/1990
LexicalTag NON
ThesaurusID NLM (1991)