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Mycophenolic Acid MeSH Descriptor Data 2022


MeSH Heading
Mycophenolic Acid
Tree Number(s)
D02.241.081.193.678
D10.251.618
Unique ID
D009173
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D009173
Scope Note
Compound derived from Penicillium stoloniferum and related species. It blocks de novo biosynthesis of purine nucleotides by inhibition of the enzyme inosine monophosphate dehydrogenase (IMP DEHYDROGENASE). Mycophenolic acid exerts selective effects on the immune system in which it prevents the proliferation of T-CELLS, LYMPHOCYTES, and the formation of antibodies from B-CELLS. It may also inhibit recruitment of LEUKOCYTES to sites of INFLAMMATION.
Entry Term(s)
Cellcept
Mycophenolate Mofetil
Mycophenolate Mofetil Hydrochloride
Mycophenolate Sodium
Mycophenolic Acid Morpholinoethyl Ester
Myfortic
RS 61443
RS-61443
Sodium Mycophenolate
Pharm Action
Antibiotics, Antineoplastic
Antibiotics, Antitubercular
Enzyme Inhibitors
Registry Number
HU9DX48N0T
Related Numbers
128794-94-5
24280-93-1
9242ECW6R0
UXH81S8ZVB
WX877SQI1G
CAS Type 1 Name
-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-, (E)-
Previous Indexing
Antibiotics, Antineoplastic (1967-1971)
Caproates (1967-1971)
Public MeSH Note
2017; MYCOPHENOLATE MOFETIL was indexed under MYCOPHENOLIC ACID 1990-2016
History Note
2017 (1999)
Date Established
1973/01/01
Date of Entry
1999/01/01
Revision Date
2016/07/11
Mycophenolic Acid Preferred
Mycophenolate Mofetil Narrower
Cellcept Narrower
Mycophenolate Sodium Narrower
Myfortic Narrower
Mycophenolate Mofetil Hydrochloride Narrower
RS 61443 Narrower
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