MeSH Browser

MeSH Heading: Bortezomib
Tree Number(s): D01.029.260.110.500; D01.132.285.500; D02.203.200.500; D03.383.679.450
Unique ID: D000069286
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000069286
Scope Note: A pyrazine and boronic acid derivative that functions as a reversible PROTEASOME INHIBITOR. It is used as an ANTINEOPLASTIC AGENT in the treatment of MULTIPLE MYELOMA and MANTLE CELL LYMPHOMA.
Entry Term(s): LDP-341; PS 341; PS-341; Velcade
Pharm Action: Antineoplastic Agents
Registry Numbers: 69G8BD63PP; 0
Related Numbers: 179324-69-7
Public MeSH Note: 2016; BORTEZOMIB was indexed under BORONIC ACIDS and PYRAZINES 2000-2015
History Note: 2016 (2000)
Date Established: 2016/01/01
Date of Entry: 2015/07/01
Revision Date: 2016/05/27

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Bortezomib MeSH Descriptor Data 2025