Discoidin Domain Receptor 1 MeSH Descriptor Data 2025

MeSH Heading: Discoidin Domain Receptor 1
Tree Number(s): D08.811.913.696.620.682.725.400.005.500; D12.776.476.568.400.005.500; D12.776.543.750.630.005.500; D12.776.543.750.685.050.500; D12.776.543.750.705.880.300.500
Unique ID: D000070819
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000070819
Scope Note: A discoidin domain receptor for FIBRILLAR COLLAGEN that functions in a variety of cellular processes. For example, it regulates cell attachment to the EXTRACELLULAR MATRIX, remodeling of the extracellular matrix, CELL MIGRATION; CELL DIFFERENTIATION; CELL PROLIFERATION; and CELL SURVIVAL.
Entry Term(s): CD167 Antigen; DDR1 Protein; Discoidin Domain Receptor Family, Member 1 Protein; Discoidin Domain Receptor Tyrosine Kinase 1
Registry Numbers: EC 2.7.10.1
Public MeSH Note: 2017; DISCOIDIN DOMAIN RECEPTOR 1 was indexed under RECEPTORS, MITOGEN and RECEPTOR PROTEIN-TYROSINE KINASES 1999-2016
History Note: 2017 (1999)
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2021/05/21

Allowable Qualifiers: administration & dosage (AD)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

physiology (PH)

radiation effects (RE)

therapeutic use (TU)

ultrastructure (UL)

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Transferases [D08.811.913]
    - Phosphotransferases [D08.811.913.696]
      - Phosphotransferases (Alcohol Group Acceptor) [D08.811.913.696.620]
        
        Protein Kinases [D08.811.913.696.620.682]
        
        Protein-Tyrosine Kinases [D08.811.913.696.620.682.725]
        
        Receptor Protein-Tyrosine Kinases [D08.811.913.696.620.682.725.400]
        
        Discoidin Domain Receptors [D08.811.913.696.620.682.725.400.005]
        
        Discoidin Domain Receptor 1 [D08.811.913.696.620.682.725.400.005.500]
        
        Discoidin Domain Receptor 2 [D08.811.913.696.620.682.725.400.005.750]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Intracellular Signaling Peptides and Proteins [D12.776.476]
    - Protein-Tyrosine Kinases [D12.776.476.568]
      - Receptor Protein-Tyrosine Kinases [D12.776.476.568.400]
        
        Discoidin Domain Receptors [D12.776.476.568.400.005]
        
        Discoidin Domain Receptor 1 [D12.776.476.568.400.005.500]
        
        Discoidin Domain Receptor 2 [D12.776.476.568.400.005.750]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Receptors, Cell Surface [D12.776.543.750]
      - Receptor Protein-Tyrosine Kinases [D12.776.543.750.630]
        
        Discoidin Domain Receptors [D12.776.543.750.630.005]
        
        Discoidin Domain Receptor 1 [D12.776.543.750.630.005.500]
        
        Discoidin Domain Receptor 2 [D12.776.543.750.630.005.750]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Receptors, Cell Surface [D12.776.543.750]
      - Receptors, Collagen [D12.776.543.750.685]
        
        Discoidin Domain Receptors [D12.776.543.750.685.050]
        
        Discoidin Domain Receptor 1 [D12.776.543.750.685.050.500]
        
        Discoidin Domain Receptor 2 [D12.776.543.750.685.050.750]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Receptors, Cell Surface [D12.776.543.750]
      - Receptors, Immunologic [D12.776.543.750.705]
        
        Receptors, Mitogen [D12.776.543.750.705.880]
        
        Discoidin Domain Receptors [D12.776.543.750.705.880.300]
        
        Discoidin Domain Receptor 1 [D12.776.543.750.705.880.300.500]
        
        Discoidin Domain Receptor 2 [D12.776.543.750.705.880.300.750]

Discoidin Domain Receptor 1 Preferred

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