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Small Fiber Neuropathy MeSH Descriptor Data 2025


MeSH Heading
Small Fiber Neuropathy
Tree Number(s)
C10.668.829.860
Unique ID
D000071075
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000071075
Scope Note
Disorder of the peripheral nerves that primarily impair small nerve fibers. The affected small nerve fibers include myelinated A-delta fibers (see A FIBERS) and unmyelinated C FIBERS. Because these small fibers innervate skin and help control autonomic function, their neuropathy presents with neuropathic pain, reduced thermal and pain sensitivity, and autonomic dysfunction (e.g. abnormal sweating or facial flushing). Small fiber neuropathy can be idiopathic or associated with underlying diseases (e.g., AMYLOIDOSIS; DIABETES MELLITUS; SARCOIDOSIS; or VASCULITIS).
Entry Term(s)
Small Fibre Neuropathy
Small Nerve Fiber Neuropathy
Public MeSH Note
2017; see ERYTHROMELALGIA 2014-2016
History Note
2017; use ERYTHROMELALGIA 2014-2016
Date Established
2017/01/01
Date of Entry
2016/07/05
Revision Date
2016/02/26
Small Fiber Neuropathy Preferred
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