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ADAMTS5 Protein MeSH Descriptor Data 2024


MeSH Heading
ADAMTS5 Protein
Tree Number(s)
D08.811.277.656.675.374.102.500.875
D09.400.430.500.500.875
D12.776.395.033.500.875
D12.776.860.300.085.875
Unique ID
D000071116
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000071116
Scope Note
An ADAMTS protease that contains two C-terminal thrombospondin (TS) motifs. It functions primarily as an aggrecanase, cleaving AGGRECAN in CARTILAGE, and may be involved in the destruction of aggrecan in ARTHRITIS.
Entry Term(s)
A Disintegrin And Metalloproteinase With Thrombospondin Motifs 5 Protein
ADAMTS-5 Protein
ADAMTS11 Protein
ADAMTS5 Protease
Aggrecanase-2
Registry Number
EC 3.4.24.-
Previous Indexing
ADAM Proteins (2006-2016)
Public MeSH Note
2017
History Note
2017
Date Established
2017/01/01
Date of Entry
2016/07/06
Revision Date
2016/02/26
ADAMTS5 Protein Preferred
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