MeSH Browser

MeSH Heading: Trefoil Factor-3
Tree Number(s): D12.644.937.875
Unique ID: D000071165
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000071165
Scope Note: A 59 amino acid (6.6 kDa) trefoil factor that contains a single trefoil domain. It is expressed in all tissues with MUCOUS MEMBRANES, including GOBLET CELLS of the SMALL INTESTINE and LARGE INTESTINE. It associates with MUCIN-2 in the small intestine and may regulate epithelial CELL MIGRATION and WOUND HEALING.
Entry Term(s): Intestinal Trefoil Factor; TFF3 Peptide; TFF3 Protein
Registry Numbers: 0
Public MeSH Note: 2017; TREFOIL FACTOR-3 was indexed under PEPTIDES 2006-2016; and under MUCINS and MUSCLE PROTEINS 1993-2005
History Note: 2017 (1992)
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2016/07/05

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M000613345
Registry Numbers: 0
Scope Note: A 59 amino acid (6.6 kDa) trefoil factor that contains a single trefoil domain. It is expressed in all tissues with MUCOUS MEMBRANES, including GOBLET CELLS of the SMALL INTESTINE and LARGE INTESTINE. It associates with MUCIN-2 in the small intestine and may regulate epithelial CELL MIGRATION and WOUND HEALING.
Terms: Trefoil Factor-3 Preferred Term
Term UI T000893209
Date01/05/2016
LexicalTag NON
ThesaurusID NLM (2017); TFF3 Protein
Term UI T000893210
Date01/05/2016
LexicalTag ABX
ThesaurusID NLM (2017); TFF3 Peptide
Term UI T000893211
Date01/05/2016
LexicalTag ABX
ThesaurusID NLM (2017); Intestinal Trefoil Factor
Term UI T000893213
Date01/05/2016
LexicalTag NON
ThesaurusID NLM (1992)

Trefoil Factor-3 MeSH Descriptor Data 2025