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Trefoil Factors MeSH Descriptor Data 2022


MeSH Heading
Trefoil Factors
Tree Number(s)
D12.644.937
Unique ID
D000071162
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000071162
Scope Note
A family of small peptides expressed primarily by MUCOUS MEMBRANE EPITHELIAL CELLS in vertebrates. Their structure is highly conserved and is defined by a three-leaved (trefoil) domain of 42 or 43 amino acids; it includes six cysteines that create the trefoil structure through disulfide bridges. Trefoil peptides may form dimers with each other, or associate with MUCINS and other factors. They are important for maintaining epithelial integrity and for protection from noxious agents.
Entry Term(s)
TFF Peptide
TFF Peptides
Trefoil Factor
Trefoil Factor Family Peptides
Trefoil Factor Family Proteins
Trefoil Peptide
Trefoil Peptides
Trefoil Protein
Trefoil Proteins
Registry Number
0
Previous Indexing
Mucins (1992-2016)
Peptides (1992-2016)
Public MeSH Note
2017
History Note
2017
Date Established
2017/01/01
Date of Entry
2016/07/08
Revision Date
2020/05/27
Trefoil Factors Preferred
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