- Concept UI
- M000614788
- Scope Note
- A DEAD-box RNA helicase that contains an N-terminal DEATH-LIKE DOMAIN, AAA+ ATPase domain, and C-terminal RNA HELICASE activity. It functions as an innate immune receptor through its recognition of viral nucleic acids. It also induces the expression of INTERFERON TYPE I and proinflammatory CYTOKINES. Its ligands include: 5'-triphosphorylated SINGLE-STRANDED RNA, DOUBLE-STRANDED RNA (dsRNA), and short dsRNA (less than 1 kb in length).
- Terms
-
DEAD Box Protein 58
Preferred Term
Term UI
T000895558
Date02/18/2016
LexicalTag
ACX
ThesaurusID
NLM (2017)
-
RIG-I-like Receptor 1
Term UI
T000895560
Date02/18/2016
LexicalTag
ABX
ThesaurusID
NLM (2017)
-
DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58
Term UI
T000895561
Date02/18/2016
LexicalTag
ABX
ThesaurusID
NLM (2017)
-
Probable ATP-Dependent RNA Helicase DDX58
Term UI
T000895562
Date02/18/2016
LexicalTag
ABX
ThesaurusID
NLM (2017)