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DEAD Box Protein 58 MeSH Descriptor Data 2024


MeSH Heading
DEAD Box Protein 58
Tree Number(s)
D08.811.913.696.445.735.720.249.750
Unique ID
D000071457
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000071457
Scope Note
A DEAD-box RNA helicase that contains an N-terminal DEATH-LIKE DOMAIN, AAA+ ATPase domain, and C-terminal RNA HELICASE activity. It functions as an innate immune receptor through its recognition of viral nucleic acids. It also induces the expression of INTERFERON TYPE I and proinflammatory CYTOKINES. Its ligands include: 5'-triphosphorylated SINGLE-STRANDED RNA, DOUBLE-STRANDED RNA (dsRNA), and short dsRNA (less than 1 kb in length).
Entry Term(s)
DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58
Probable ATP-Dependent RNA Helicase DDX58
RIG-I-like Receptor 1
Previous Indexing
DEAD-box RNA Helicases (2006-2016)
Public MeSH Note
2017
History Note
2017
Date Established
2017/01/01
Date of Entry
2016/07/08
Revision Date
2016/04/15
DEAD Box Protein 58 Preferred
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