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Interferon-Induced Helicase, IFIH1 MeSH Descriptor Data 2022


MeSH Heading
Interferon-Induced Helicase, IFIH1
Tree Number(s)
D08.811.913.696.445.735.720.249.875
D12.776.066.125
Unique ID
D000072640
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000072640
Scope Note
A DEAD box RNA helicase that contains two N-terminal CASPASE ACTIVATION AND RECRUITMENT DOMAINS. It functions as a sensor of viral NUCLEIC ACIDS such as DOUBLE-STRANDED RNA and activates the INNATE IMMUNE RESPONSE by inducing the expression of INTERFERON-ALPHA and INTERFERON-BETA. It may also regulate cell growth and APOPTOSIS.
Entry Term(s)
CADM-140 Autoantigen
Helicard
IFIH1 Protein
Interferon Induced with Helicase C Domain 1
Interferon-Induced Helicase C Domain-Containing Protein 1
Melanoma Differentiation-Associated Protein 5
Registry Number
EC 3.6.4.13
Previous Indexing
DEAD-box RNA Helicases (2006-2016)
Public MeSH Note
2017
History Note
2017
Date Established
2017/01/01
Date of Entry
2016/07/08
Revision Date
2021/05/10
Interferon-Induced Helicase, IFIH1 Preferred
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