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Interferon-alpha MeSH Descriptor Data 2022


MeSH Heading
Interferon-alpha
Tree Number(s)
D12.644.276.374.440.890.250
D12.776.467.374.440.890.250
D23.529.374.440.890.250
Unique ID
D016898
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D016898
Scope Note
One of the type I interferons produced by peripheral blood leukocytes or lymphoblastoid cells. In addition to antiviral activity, it activates NATURAL KILLER CELLS and B-LYMPHOCYTES, and down-regulates VASCULAR ENDOTHELIAL GROWTH FACTOR expression through PI-3 KINASE and MAPK KINASES signaling pathways.
Entry Term(s)
IFN-alpha D
IFN-alpha5
Interferon Alfa
Interferon alpha-1
Interferon alpha-17
Interferon alpha-4
Interferon alpha-5
Interferon alpha-7
Interferon alpha-88
Interferon alpha-J
Interferon alpha-T
Interferon alpha4
Interferon alpha5
Interferon, Leukocyte
Interferon, Lymphoblast
Interferon, Lymphoblastoid
Interferon, alpha
LeIF I
LeIF J
Leif D
alpha-Interferon
Pharm Action
Antiviral Agents
Immunologic Factors
Registry Number
0
Previous Indexing
Interferon Type I (1983-1991)
Public MeSH Note
1992; see INTERFERON TYPE I 1983-1991, INTERFERON ALPHA-1 was indexed under INTERFERON-ALPHA 2001-2011, INTERFERON-ALPHA 2 was indexed under INTERFERON-ALPHA 1997-2011, INTERFERON ALPHA4 was indexed under INTERFERON-ALPHA 1993-2001, INTERFERON ALPHA5 was indexed under INTERFERON-ALPHA 1996-2001
History Note
1992; for INTERFERON, LYMPHOBLAST and INTERFERON, LEUKOCYTE use INTERFERON TYPE I 1989-1991
Date Established
1992/01/01
Date of Entry
1991/05/30
Revision Date
2018/01/11
Interferon-alpha Preferred
Interferon alpha-17 Narrower
Interferon alpha-5 Narrower
Interferon alpha-7 Narrower
Interferon alpha-1 Narrower
Interferon alpha-4 Narrower
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