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APOBEC-3G Deaminase MeSH Descriptor Data 2022


MeSH Heading
APOBEC-3G Deaminase
Tree Number(s)
D08.811.277.151.486.250.500.750
D12.776.066.032
Unique ID
D000071480
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000071480
Scope Note
An APOBEC deaminase that functions as an inhibitor of RETROVIRIDAE replication and inhibits the mobility of RETROTRANSPOSONS via deaminase-dependent and independent mechanisms. It is selective for SINGLE-STRANDED DNA and does not deaminate double-stranded DNA or single or DOUBLE-STRANDED RNA. It exhibits potent antiviral activity against VIF PROTEIN deficient HIV-1 through the creation of hypermutations in the VIRAL DNA. It also has anti-viral activity against SIMIAN IMMUNODEFICIENCY VIRUSES and HEPATITIS B VIRUS.
Entry Term(s)
APOBEC-3G Protein
APOBEC-3G dC-dU Editing Enzyme
APOBEC-Related Cytidine Deaminase
APOBEC-Related Protein
APOBEC3G Deaminase
APOBEC3G Protein
CEM15 Protein
Registry Number
EC 3.5.4.5
Previous Indexing
Cytidine Deaminase (2007-2016)
Public MeSH Note
2017
History Note
2017
Date Established
2017/01/01
Date of Entry
2016/07/08
Revision Date
2021/05/10
APOBEC-3G Deaminase Preferred
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