MeSH Browser

MeSH Heading: X-Box Binding Protein 1
Tree Number(s): D12.776.260.108.937; D12.776.930.127.937
Unique ID: D000071717
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000071717
Scope Note: A basic leucine zipper transcription factor that regulates expression of MHC CLASS II GENES through its binding to a conserved X-box DNA sequence in the promoter region. It regulates the expression of genes involved in the UNFOLDED PROTEIN RESPONSE.
Entry Term(s): TREB-5 Protein; TREB5 Protein; Tax-Responsive Element-Binding Protein 5; XBP-1 Protein; XBP2 Protein
Registry Numbers: 0
Public MeSH Note: 2017; see REGULATORY FACTOR X TRANSCRIPTION FACTORS 1988-2016
History Note: 2017; use REGULATORY FACTOR X TRANSCRIPTION FACTORS (NM) 1988-2016
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2016/04/15

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M000615358
Registry Numbers: 0
Scope Note: A basic leucine zipper transcription factor that regulates expression of MHC CLASS II GENES through its binding to a conserved X-box DNA sequence in the promoter region. It regulates the expression of genes involved in the UNFOLDED PROTEIN RESPONSE.
Terms: X-Box Binding Protein 1 Preferred Term
Term UI T000896433
Date03/03/2016
LexicalTag NON
ThesaurusID NLM (2017); TREB-5 Protein
Term UI T000896435
Date03/03/2016
LexicalTag ACX
ThesaurusID NLM (2017); TREB5 Protein
Term UI T000896436
Date03/03/2016
LexicalTag ACX
ThesaurusID NLM (2017); XBP2 Protein
Term UI T000896437
Date03/03/2016
LexicalTag ABX
ThesaurusID NLM (2017); XBP-1 Protein
Term UI T000896438
Date03/03/2016
LexicalTag ABX
ThesaurusID NLM (2017); Tax-Responsive Element-Binding Protein 5
Term UI T000896434
Date03/03/2016
LexicalTag NON
ThesaurusID NLM (2017)

X-Box Binding Protein 1 MeSH Descriptor Data 2025