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ADAM12 Protein MeSH Descriptor Data 2022


MeSH Heading
ADAM12 Protein
Tree Number(s)
D08.811.277.656.675.374.102.125
D09.400.430.500.125
D12.776.395.033.125
Unique ID
D000072199
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000072199
Scope Note
A disintegrin and metalloproteinase domain-containing protein that is expressed as two alternatively-spliced forms: a long transmembrane form (ADAM12-L) and a short soluble form (ADAM12-S). It modulates the cleavage of INSULIN-LIKE GROWTH FACTOR BINDING PROTEINS and may also regulate CELL FUSION during MYOGENESIS.
Entry Term(s)
ADAM 12 Protein
ADAM-12 Protein
ADAM12-L Protein
ADAM12-S Protein
Disintegrin and Metalloproteinase Domain-Containing Protein 12
Meltrin-alpha Protein
Registry Number
EC 3.4.24.-
Related Numbers
EC 3.4.24.82
Public MeSH Note
2017; ADAM12 PROTEIN was indexed under MEMBRANE PROTEINS and ADAM PROTEINS 2006-2016; and under METALLOENDOPEPTIDASES 1997-2005
History Note
2017 (1997)
Date Established
2017/01/01
Date of Entry
2016/07/06
Revision Date
2016/05/27
ADAM12 Protein Preferred
ADAM12-S Protein Narrower
ADAM12-L Protein Narrower
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