- Concept UI
- M000625733
- Registry Numbers
- 0
- Scope Note
- A secreted serine peptidase inhibitor that consists of 15 KAZAL MOTIFS and inhibits KALLIKREINS KLK5, KLK7, and KLK14 as well as TRYPSIN. It plays important roles in protecting MUCOSA against infection and inflammation, and in maintaining the integrity of the skin. Mutations in the SPINK5 gene are associated with NETHERTON SYNDROME.
- Terms
-
Serine Peptidase Inhibitor Kazal-Type 5
Preferred Term
Term UI
T000914372
Date01/19/2017
LexicalTag
NON
ThesaurusID
NLM (2018)
-
Serine Protease Inhibitor Kazal-Type 5
Term UI
T000914371
Date01/19/2017
LexicalTag
NON
ThesaurusID
NLM (2018)
-
Lympho-Epithelial Kazal-Type Inhibitor
Term UI
T000914373
Date01/19/2017
LexicalTag
NON
ThesaurusID
NLM (2018)
-
SPINK5 Protein
Term UI
T000914374
Date01/19/2017
LexicalTag
ACX
ThesaurusID
NLM (2018)
-
LEKTI Protein
Term UI
T000914375
Date01/19/2017
LexicalTag
ACX
ThesaurusID
NLM (2018)