MeSH Browser

MeSH Heading: Anoctamin-1
Tree Number(s): D12.776.157.530.400.175.032.500; D12.776.543.550.450.175.032.500; D12.776.543.585.400.175.032.500
Unique ID: D000075369
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000075369
Scope Note: An anoctamin chloride channel expressed at high levels in the liver, skeletal muscle, and gastrointestinal muscles that functions in transepithelial anion transport and smooth muscle contraction. It is essential for the function of the INTERSTITIAL CELLS OF CAJAL and plays a major role in chloride conduction by airway epithelial cells and in tracheal cartilage development.
Entry Term(s): TMEM16A Protein; Transmembrane Protein 16A
Registry Numbers: 0
Previous Indexing: Chloride Channels (2003-2017)
Public MeSH Note: 2018
History Note: 2018
Date Established: 2018/01/01
Date of Entry: 2017/07/11
Revision Date: 2017/05/24

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M000630246
Registry Numbers: 0
Scope Note: An anoctamin chloride channel expressed at high levels in the liver, skeletal muscle, and gastrointestinal muscles that functions in transepithelial anion transport and smooth muscle contraction. It is essential for the function of the INTERSTITIAL CELLS OF CAJAL and plays a major role in chloride conduction by airway epithelial cells and in tracheal cartilage development.
Terms: Anoctamin-1 Preferred Term
Term UI T000921934
Date04/18/2017
LexicalTag NON
ThesaurusID NLM (2018); TMEM16A Protein
Term UI T000921935
Date04/18/2017
LexicalTag ABX
ThesaurusID NLM (2018); Transmembrane Protein 16A
Term UI T000921936
Date04/18/2017
LexicalTag NON
ThesaurusID NLM (2018)

Anoctamin-1 MeSH Descriptor Data 2025