MeSH Browser

MeSH Heading: Anoctamins
Tree Number(s): D12.776.157.530.400.175.032; D12.776.543.550.450.175.032; D12.776.543.585.400.175.032
Unique ID: D000075368
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000075368
Scope Note: A family of transmembrane proteins that function primarily as calcium-activated chloride channels. Structurally, they form a homodimer where each subunit consists of eight transmembrane helices with the N and C terminals exposed to the cytosol. The regions between helices 5 and 7 may be important for ion pore formation and calcium ion binding.
Entry Term(s): Anoctamin; TMEM16 Protein Family; TMEM16 Proteins
Registry Numbers: 0
Previous Indexing: Chloride Channels (2009-2017)
Public MeSH Note: 2018
History Note: 2018
Date Established: 2018/01/01
Date of Entry: 2017/07/11
Revision Date: 2017/05/24

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M000630244
Registry Numbers: 0
Scope Note: A family of transmembrane proteins that function primarily as calcium-activated chloride channels. Structurally, they form a homodimer where each subunit consists of eight transmembrane helices with the N and C terminals exposed to the cytosol. The regions between helices 5 and 7 may be important for ion pore formation and calcium ion binding.
Terms: Anoctamins Preferred Term
Term UI T000921929
Date04/18/2017
LexicalTag NON
ThesaurusID NLM (2018); TMEM16 Proteins
Term UI T000921930
Date04/18/2017
LexicalTag ABX
ThesaurusID NLM (2018); Anoctamin
Term UI T000921932
Date04/18/2017
LexicalTag NON
ThesaurusID NLM (2018); TMEM16 Protein Family
Term UI T000921933
Date04/18/2017
LexicalTag NON
ThesaurusID NLM (2018)

Anoctamins MeSH Descriptor Data 2025