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Anoctamins MeSH Descriptor Data 2022


MeSH Heading
Anoctamins
Tree Number(s)
D12.776.157.530.400.175.032
D12.776.543.550.450.175.032
D12.776.543.585.400.175.032
Unique ID
D000075368
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000075368
Scope Note
A family of transmembrane proteins that function primarily as calcium-activated chloride channels. Structurally, they form a homodimer where each subunit consists of eight transmembrane helices with the N and C terminals exposed to the cytosol. The regions between helices 5 and 7 may be important for ion pore formation and calcium ion binding.
Entry Term(s)
Anoctamin
TMEM16 Protein Family
TMEM16 Proteins
Registry Number
0
Previous Indexing
Chloride Channels (2009-2017)
Public MeSH Note
2018
History Note
2018
Date Established
2018/01/01
Date of Entry
2017/07/11
Revision Date
2017/05/24
Anoctamins Preferred
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