A transcriptional activator that contains five adjacent CYS2-HIS2 ZINC FINGERS. It functions in the hedgehog signaling pathway and is required for normal embryonic development. Mutations in the GLI2 gene are associated with type 9 HOLOPROSENCEPHALY and type 2 PALLISTER-HALL SYNDROME.
2018; see GLI2 PROTEIN 1997-2017; ZINC FINGER PROTEIN GLI2 was indexed under KRUPPEL-LIKE TRANSCRIPTION FACTORS 2006-2017; under TRANSCRIPTION FACTORS 1999-2005; and under PROTEINS 1997-1998
A transcriptional activator that contains five adjacent CYS2-HIS2 ZINC FINGERS. It functions in the hedgehog signaling pathway and is required for normal embryonic development. Mutations in the GLI2 gene are associated with type 9 HOLOPROSENCEPHALY and type 2 PALLISTER-HALL SYNDROME.