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Simendan MeSH Descriptor Data 2022


MeSH Heading
Simendan
Tree Number(s)
D02.442.288.610
D03.383.710.802
Unique ID
D000077464
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000077464
Scope Note
A hydrazone and pyridazine derivative; the levo-form is a phosphodiesterase III inhibitor, calcium-sensitizing agent, and inotropic agent that is used in the treatment of HEART FAILURE.
Entry Term(s)
((4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl)hydrazono)propanedinitrile
Dextrosimendan
Levosimendan
OR 1259
OR-1259
OR-1855
Simadax
Pharm Action
Cardiotonic Agents
Vasodilator Agents
Phosphodiesterase 3 Inhibitors
Registry Number
349552KRHK
Related Numbers
131741-08-7
C6T4514L4E
CAS Type 1 Name
Propanedinitrile, 2-(2-(4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl)hydrazinylidene)-
Public MeSH Note
2019; SIMENDAN was indexed under HYDRAZONES and PYRIDAZINES 1992-2018
History Note
2019 (1992)
Date Established
2019/01/01
Date of Entry
2018/07/09
Revision Date
2018/07/03
Simendan Preferred
Simadax Narrower
Dextrosimendan Narrower
OR 1259 Narrower
Levosimendan Narrower
OR-1855 Narrower
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