MeSH Browser

MeSH Heading: Cilazapril
Tree Number(s): D03.383.710.100
Unique ID: D017315
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D017315
Scope Note: One of the ANGIOTENSIN-CONVERTING ENZYME INHIBITORS (ACE inhibitors) used for hypertension. It is a prodrug that is hydrolyzed after absorption to its main metabolite cilazaprilat.
Entry Term(s): Cilazapril Anhydrous; Cilazapril Hydrate; Cilazapril Monohydrate; Cilazapril Monohydrobromide; Cilazapril, (S*)-Isomer; Cilazapril, Anhydrous; Inhibace; Ro 31-2848; Ro-31-2848
Pharm Action: Angiotensin-Converting Enzyme Inhibitors
Antihypertensive Agents
Related Numbers: 106928-09-0; 116299-83-3; 8Q9454114Q; 92077-78-6
CAS Type 1 Name: 6H-Pyridazino(1,2-a)(1,2)diazepine-1-carboxylic acid, 9-(((1S)-1-(ethoxycarbonyl)-3-phenylpropyl)amino)octahydro-10-oxo-, (1S,9S)-
Previous Indexing: Pyridazines (1984-1992)
Public MeSH Note: 1993; CILAZAPRIL was indexed under PYRIDAZINES 1984-1992
History Note: 1993 (1984)
Date Established: 1993/01/01
Date of Entry: 1992/05/07
Revision Date: 2018/02/28

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Cilazapril MeSH Descriptor Data 2024