MeSH Browser

MeSH Heading: Panitumumab
Tree Number(s): D12.776.124.486.485.114.224.060.864; D12.776.124.790.651.114.224.060.864; D12.776.377.715.548.114.224.200.864
Unique ID: D000077544
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000077544
Scope Note: Recombinant human monoclonal antibody that binds to and inhibits the function of the EPIDERMAL GROWTH FACTOR RECEPTOR. It is used in the treatment of EGFR-expressing metastatic colorectal cancer that expresses wild-type ras gene (see GENES, RAS).
Entry Term(s): ABX-EGF MAb; ABX-EGF Monoclonal Antibody; Panitumumab Antibody, Human; Vectibix
Pharm Action: Antineoplastic Agents, Immunological
Registry Numbers: 6A901E312A; 0
CAS Type 1 Name: Immunoglobulin, anti-(human epidermal growth factor receptor) (human monoclonal ABX-EGF heavy chain), disulfide with human monoclonal ABX-EGF light chain, dimer
Public MeSH Note: 2019; PANITUMUMAB was indexed under ANTIBODIES, MONOCLONAL 2005-2018
History Note: 2019 (2005)
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2018/04/09

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemistry (CH)

classification (CL)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Blood Proteins [D12.776.124]
    - Immunoproteins [D12.776.124.486]
      - Immunoglobulins [D12.776.124.486.485]
        
        Antibodies [D12.776.124.486.485.114]
        
        Antibodies, Monoclonal [D12.776.124.486.485.114.224]
        
        Antibodies, Monoclonal, Humanized [D12.776.124.486.485.114.224.060]
        
        Abciximab [D12.776.124.486.485.114.224.060.125]
        
        Adalimumab [D12.776.124.486.485.114.224.060.250]
        
        Alemtuzumab [D12.776.124.486.485.114.224.060.313]
        
        Basiliximab [D12.776.124.486.485.114.224.060.344]
        
        Bevacizumab [D12.776.124.486.485.114.224.060.375]
        
        Brentuximab Vedotin [D12.776.124.486.485.114.224.060.438]
        
        Certolizumab Pegol [D12.776.124.486.485.114.224.060.500]
        
        Cetuximab [D12.776.124.486.485.114.224.060.750]
        
        Daclizumab [D12.776.124.486.485.114.224.060.766]
        
        Denosumab [D12.776.124.486.485.114.224.060.782]
        
        Gemtuzumab [D12.776.124.486.485.114.224.060.790]
        
        Inotuzumab Ozogamicin [D12.776.124.486.485.114.224.060.794]
        
        Ipilimumab [D12.776.124.486.485.114.224.060.798]
        
        Natalizumab [D12.776.124.486.485.114.224.060.813]
        
        Nivolumab [D12.776.124.486.485.114.224.060.829]
        
        Omalizumab [D12.776.124.486.485.114.224.060.844]
        
        Palivizumab [D12.776.124.486.485.114.224.060.860]
        
        Panitumumab [D12.776.124.486.485.114.224.060.864]
        
        Ramucirumab [D12.776.124.486.485.114.224.060.866]
        
        Ranibizumab [D12.776.124.486.485.114.224.060.868]
        
        Trastuzumab [D12.776.124.486.485.114.224.060.875]
        
        Ustekinumab [D12.776.124.486.485.114.224.060.937]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Blood Proteins [D12.776.124]
    - Serum Globulins [D12.776.124.790]
      - Immunoglobulins [D12.776.124.790.651]
        
        Antibodies [D12.776.124.790.651.114]
        
        Antibodies, Monoclonal [D12.776.124.790.651.114.224]
        
        Antibodies, Monoclonal, Humanized [D12.776.124.790.651.114.224.060]
        
        Abciximab [D12.776.124.790.651.114.224.060.125]
        
        Adalimumab [D12.776.124.790.651.114.224.060.250]
        
        Alemtuzumab [D12.776.124.790.651.114.224.060.375]
        
        Basiliximab [D12.776.124.790.651.114.224.060.407]
        
        Bevacizumab [D12.776.124.790.651.114.224.060.438]
        
        Brentuximab Vedotin [D12.776.124.790.651.114.224.060.469]
        
        Certolizumab Pegol [D12.776.124.790.651.114.224.060.500]
        
        Cetuximab [D12.776.124.790.651.114.224.060.750]
        
        Daclizumab [D12.776.124.790.651.114.224.060.766]
        
        Denosumab [D12.776.124.790.651.114.224.060.782]
        
        Gemtuzumab [D12.776.124.790.651.114.224.060.790]
        
        Inotuzumab Ozogamicin [D12.776.124.790.651.114.224.060.794]
        
        Ipilimumab [D12.776.124.790.651.114.224.060.798]
        
        Natalizumab [D12.776.124.790.651.114.224.060.813]
        
        Nivolumab [D12.776.124.790.651.114.224.060.829]
        
        Omalizumab [D12.776.124.790.651.114.224.060.844]
        
        Palivizumab [D12.776.124.790.651.114.224.060.860]
        
        Panitumumab [D12.776.124.790.651.114.224.060.864]
        
        Ramucirumab [D12.776.124.790.651.114.224.060.866]
        
        Ranibizumab [D12.776.124.790.651.114.224.060.868]
        
        Trastuzumab [D12.776.124.790.651.114.224.060.875]
        
        Ustekinumab [D12.776.124.790.651.114.224.060.937]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Globulins [D12.776.377]
    - Serum Globulins [D12.776.377.715]
      - Immunoglobulins [D12.776.377.715.548]
        
        Antibodies [D12.776.377.715.548.114]
        
        Antibodies, Monoclonal [D12.776.377.715.548.114.224]
        
        Antibodies, Monoclonal, Humanized [D12.776.377.715.548.114.224.200]
        
        Abciximab [D12.776.377.715.548.114.224.200.125]
        
        Adalimumab [D12.776.377.715.548.114.224.200.250]
        
        Alemtuzumab [D12.776.377.715.548.114.224.200.375]
        
        Basiliximab [D12.776.377.715.548.114.224.200.407]
        
        Bevacizumab [D12.776.377.715.548.114.224.200.438]
        
        Brentuximab Vedotin [D12.776.377.715.548.114.224.200.469]
        
        Certolizumab Pegol [D12.776.377.715.548.114.224.200.500]
        
        Cetuximab [D12.776.377.715.548.114.224.200.750]
        
        Daclizumab [D12.776.377.715.548.114.224.200.766]
        
        Denosumab [D12.776.377.715.548.114.224.200.782]
        
        Gemtuzumab [D12.776.377.715.548.114.224.200.790]
        
        Inotuzumab Ozogamicin [D12.776.377.715.548.114.224.200.794]
        
        Ipilimumab [D12.776.377.715.548.114.224.200.798]
        
        Natalizumab [D12.776.377.715.548.114.224.200.813]
        
        Nivolumab [D12.776.377.715.548.114.224.200.829]
        
        Omalizumab [D12.776.377.715.548.114.224.200.844]
        
        Palivizumab [D12.776.377.715.548.114.224.200.860]
        
        Panitumumab [D12.776.377.715.548.114.224.200.864]
        
        Ramucirumab [D12.776.377.715.548.114.224.200.866]
        
        Ranibizumab [D12.776.377.715.548.114.224.200.868]
        
        Trastuzumab [D12.776.377.715.548.114.224.200.875]
        
        Ustekinumab [D12.776.377.715.548.114.224.200.937]

Panitumumab Preferred

Concept UI: M0484911
Registry Numbers: 6A901E312A
Scope Note: Recombinant human monoclonal antibody that binds to and inhibits the function of the EPIDERMAL GROWTH FACTOR RECEPTOR. It is used in the treatment of EGFR-expressing metastatic colorectal cancer that expresses wild-type ras gene (see GENES, RAS).
Terms: Panitumumab Preferred Term
Term UI T000940095
Date02/06/2018
LexicalTag NON
ThesaurusID; ABX-EGF MAb
Term UI T460764
Date09/09/2001
LexicalTag ABB
ThesaurusID NLM (2001); ABX-EGF Monoclonal Antibody
Term UI T000940096
Date02/06/2018
LexicalTag NON
ThesaurusID NLM (2001); Panitumumab Antibody, Human
Term UI T000940097
Date02/06/2018
LexicalTag NON
ThesaurusID NLM (2005)

Vectibix Narrower

Panitumumab MeSH Descriptor Data 2025