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Abciximab MeSH Descriptor Data 2022


MeSH Heading
Abciximab
Tree Number(s)
D12.644.541.500.650.125
D12.776.124.486.485.114.224.060.125
D12.776.124.486.485.680.650.125
D12.776.124.790.651.114.224.060.125
D12.776.124.790.651.680.650.125
D12.776.377.715.548.114.224.200.125
D12.776.377.715.548.680.650.125
Unique ID
D000077284
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000077284
Scope Note
A Fab fragment of the chimeric monoclonal antibody 7E3 that binds to the glycoprotein IIb-IIIa receptor of human platelets, and blocks PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX, potently inhibiting PLATELET AGGREGATION. It is used in treatment of refractory unstable angina, and for prevention of ischemic complications in patients undergoing percutaneous coronary procedures such as ANGIOPLASTY; ATHERECTOMY; or stenting.
Entry Term(s)
CentoRx
Chimeric 7E3 Fab
Clotinab
ReoPro
c7E3 Fab
Pharm Action
Anticoagulants
Platelet Aggregation Inhibitors
Registry Number
X85G7936GV
Related Numbers
143653-53-6
Public MeSH Note
2019; ABCIXIMAB was indexed under ANTIBODIES, MONOCLONAL and IMMUNOGLOBULIN FAB FRAGMENTS 1994-2018
History Note
2019 (1994)
Date Established
2019/01/01
Date of Entry
2018/07/09
Revision Date
2018/02/27
Abciximab Preferred
ReoPro Narrower
Clotinab Narrower
CentoRx Narrower
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