- Concept UI
- M0011126
- Registry Numbers
- 0
- Scope Note
- Univalent antigen-binding fragments composed of one entire IMMUNOGLOBULIN LIGHT CHAIN and the amino terminal end of one of the IMMUNOGLOBULIN HEAVY CHAINS from the hinge region, linked to each other by disulfide bonds. Fab contains the IMMUNOGLOBULIN VARIABLE REGIONS, which are part of the antigen-binding site, and the first IMMUNOGLOBULIN CONSTANT REGIONS. This fragment can be obtained by digestion of immunoglobulins with the proteolytic enzyme PAPAIN.
- Terms
-
Immunoglobulin Fab Fragments
Preferred Term
Term UI
T633956
Date03/22/2005
LexicalTag
NON
ThesaurusID
NLM (2006)
-
Ig Fab Fragments
Term UI
T000962317
Date06/25/2019
LexicalTag
ABX
ThesaurusID
NLM (2020)
-
Fab Fragments
Term UI
T021383
Date03/15/1991
LexicalTag
NON
ThesaurusID
NLM (1992)
-
Immunoglobulins, Fab
Term UI
T021382
Date01/01/1999
LexicalTag
ACX
ThesaurusID
NLM (1973)
-
Immunoglobulin Fab Fragment
Term UI
T633959
Date03/22/2005
LexicalTag
NON
ThesaurusID
NLM (2006)
-
Fab Immunoglobulin Fragments
Term UI
T634137
Date03/23/2005
LexicalTag
NON
ThesaurusID
NLM (2006)
-
Immunoglobulins, Fab Fragment
Term UI
T634138
Date03/23/2005
LexicalTag
NON
ThesaurusID
NLM (2006)
-
Fab Fragment
Term UI
T001081132
Date05/22/2020
LexicalTag
NON
ThesaurusID
NLM (2021)