MeSH Browser

MeSH Heading: Immunoglobulin Idiotypes
Tree Number(s): D12.644.541.500.745; D12.776.124.486.485.680.745; D12.776.124.790.651.680.745; D12.776.377.715.548.680.745; D23.050.550.750; G02.111.570.060.425.580; G12.500.450
Unique ID: D007130
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D007130
Scope Note: Unique genetically-controlled determinants present on ANTIBODIES whose specificity is limited to a single group of proteins (e.g., another antibody molecule or an individual myeloma protein). The idiotype appears to represent the antigenicity of the antigen-binding site of the antibody and to be genetically codetermined with it. The idiotypic determinants have been precisely located to the IMMUNOGLOBULIN VARIABLE REGION of both immunoglobin polypeptide chains.
Entry Version: IG IDIOTYPES
Entry Term(s): Idiotypes, Immunoglobulin; Ig Idiotypes
Pharm Action: Immunologic Factors
Registry Numbers: 0
NLM Classification #: QW 601
Previous Indexing: Anti-Antibodies (1966-1969); Antibody Specificity (1970-1978); Antigenic Determinants (1970-1978); Binding Sites, Antibody (1973-1978)
Public MeSH Note: 79
History Note: 79
Date Established: 1979/01/01
Date of Entry: 1978/01/27
Revision Date: 2019/07/05

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemistry (CH)

classification (CL)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0011109
Registry Numbers: 0
Scope Note: Unique genetically-controlled determinants present on ANTIBODIES whose specificity is limited to a single group of proteins (e.g., another antibody molecule or an individual myeloma protein). The idiotype appears to represent the antigenicity of the antigen-binding site of the antibody and to be genetically codetermined with it. The idiotypic determinants have been precisely located to the IMMUNOGLOBULIN VARIABLE REGION of both immunoglobin polypeptide chains.
Terms: Immunoglobulin Idiotypes Preferred Term
Term UI T021340
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1979); Ig Idiotypes
Term UI T000952305
Date03/01/2019
LexicalTag NON
ThesaurusID NLM (2020); Idiotypes, Immunoglobulin
Term UI T021339
Date01/27/1978
LexicalTag NON
ThesaurusID UNK (19XX)

Immunoglobulin Idiotypes MeSH Descriptor Data 2025