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Complementarity Determining Regions MeSH Descriptor Data 2023


MeSH Heading
Complementarity Determining Regions
Tree Number(s)
D12.644.541.500.650.500.180
D12.776.124.486.485.680.650.500.180
D12.776.124.486.485.797.180
D12.776.124.790.651.680.650.500.180
D12.776.124.790.651.797.180
D12.776.377.715.548.680.650.500.180
D12.776.377.715.548.797.180
D12.776.543.750.705.816.824.300
G02.111.570.060.425.160
Unique ID
D022801
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D022801
Scope Note
Three regions (CDR1; CDR2 and CDR3) of amino acid sequence in the IMMUNOGLOBULIN VARIABLE REGION that are highly divergent. Together the CDRs from the light and heavy immunoglobulin chains form a surface that is complementary to the antigen. These regions are also present in other members of the immunoglobulin superfamily, for example, T-cell receptors (RECEPTORS, ANTIGEN, T-CELL).
Entry Term(s)
Complementarity Determining Region
Complementarity Determining Region 1
Complementarity Determining Region 2
Complementarity Determining Region 3
Complementarity Determining Region I
Complementarity Determining Region II
Complementarity Determining Region III
Complementarity-Determining Region
Complementarity-Determining Region 3
Hypervariable Region, Immunoglobulin
Hypervariable Regions, Immunoglobulin
Third Complementarity-Determining Region
Registry Number
0
Previous Indexing
Immunoglobulin Variable Region (1982-2000)
See Also
Receptors, Antigen, T-Cell
Public MeSH Note
2001; for COMPLEMENTARITY DETERMINING REGION and HYPERVARIABLE REGION see IMMUNOGLOBULIN VARIABLE REGION 1988-2000; COMPLEMENTARITY-DETERMINING REGION 3 was indexed under COMPLEMENTARITY DETERMINING REGIONS 1998-2005
History Note
2001; for COMPLEMENTARITY DETERMINING REGION and HYPERVARIABLE REGION use IMMUNOGLOBULIN VARIABLE REGION 1988-2000
Date Established
2001/01/01
Date of Entry
2000/06/22
Revision Date
2011/06/24
Complementarity Determining Regions Preferred
Complementarity Determining Region 3 Narrower
Complementarity Determining Region 1 Narrower
Complementarity Determining Region 2 Narrower
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