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Immunoglobulin Joining Region MeSH Descriptor Data 2023


MeSH Heading
Immunoglobulin Joining Region
Tree Number(s)
D12.644.541.500.650.500.590
D12.776.124.486.485.680.650.500.590
D12.776.124.486.485.797.590
D12.776.124.790.651.680.650.500.590
D12.776.124.790.651.797.590
D12.776.377.715.548.680.650.500.590
D12.776.377.715.548.797.590
Unique ID
D007133
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D007133
Scope Note
A segment of the immunoglobulin heavy chains, encoded by the IMMUNOGLOBULIN HEAVY CHAIN GENES in the J segment where, during the maturation of B-LYMPHOCYTES; the gene segment for the variable region upstream is joined to a constant region gene segment downstream. The exact position of joining of the two gene segments is variable and contributes to ANTIBODY DIVERSITY. It is distinguished from the IMMUNOGLOBULIN J CHAINS; a separate polypeptide that serves as a linkage piece in polymeric IGA or IGM.
Entry Term(s)
Immunoglobulin Joining Region Peptide Fragments
Joining Region, Ig
Pharm Action
Immunologic Factors
Registry Number
0
Previous Indexing
Amino Acid Sequence (1971-1987)
Immunoglobulin Constant Region (1979-1987)
Immunoglobulin Variable Region (1977-1987)
Immunoglobulins, Heavy Chain (1977-1987)
See Also
Genes, Immunoglobulin
Public MeSH Note
88
History Note
88
Date Established
1988/01/01
Date of Entry
1987/05/11
Revision Date
2010/06/25
Immunoglobulin Joining Region Preferred
Immunoglobulin Joining Region Peptide Fragments Related
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