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Immunoglobulin Fc Fragments MeSH Descriptor Data 2023


MeSH Heading
Immunoglobulin Fc Fragments
Tree Number(s)
D12.644.541.500.697
D12.776.124.486.485.538.500
D12.776.124.486.485.680.697
D12.776.124.790.651.538.500
D12.776.124.790.651.680.660
D12.776.377.715.548.538.500
D12.776.377.715.548.680.660
Unique ID
D007141
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D007141
Scope Note
Crystallizable fragments composed of the carboxy-terminal halves of both IMMUNOGLOBULIN HEAVY CHAINS linked to each other by disulfide bonds. Fc fragments contain the carboxy-terminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (COMPLEMENT fixation, binding to the cell membrane via FC RECEPTORS, and placental transport). This fragment can be obtained by digestion of immunoglobulins with the proteolytic enzyme PAPAIN.
Entry Version
IG FC FRAGMENTS
Entry Term(s)
Fc Fragment
Fc Fragments
Fc Immunoglobulin
Fc Immunoglobulins
Ig Fc Fragments
Immunoglobulin Fc Fragment
Immunoglobulins, Fc
Immunoglobulins, Fc Fragment
Pharm Action
Immunologic Factors
Registry Number
0
Previous Indexing
Immunoglobulins (1970-1972)
See Also
Receptors, Fc
Public MeSH Note
2006; see IMMUNOGLOBULINS, FC 1987-2005, see IMMUNOGLOBULIN FRAGMENTS 1984-1986, see IMMUNOGLOBULINS, FC 1973-1983
History Note
2006 (1973)
Date Established
1973/01/01
Date of Entry
1999/01/01
Revision Date
2021/06/30
Immunoglobulin Fc Fragments Preferred
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