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Afatinib MeSH Descriptor Data 2022


MeSH Heading
Afatinib
Tree Number(s)
D02.065.132
D03.633.100.786.188
Unique ID
D000077716
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000077716
Scope Note
A quinazoline and butenamide derivative that acts as a tyrosine kinase inhibitor of epidermal growth factor receptors (ERBB RECEPTORS) and is used in the treatment of metastatic NON-SMALL CELL LUNG CANCER.
Entry Term(s)
(2E)-N-(4-(3-Chloro-4-fluoroanilino)-7-(((3S)-oxolan-3-yl)oxy)quinoxazolin-6-yl)-4-(dimethylamino)but-2-enamide
Afatinib Dimaleate
Afatinib Maleate
BIBW 2992
BIBW-2992
BIBW-2992-MA2
BIBW-2992MA2
BIBW2992
BIBW2992 MA2
Gilotrif
Pharm Action
Antineoplastic Agents
Protein Kinase Inhibitors
Registry Number
41UD74L59M
Related Numbers
850140-72-6
V1T5K7RZ0B
CAS Type 1 Name
2-Butenamide, N-(4-((3-chloro-4-fluorophenyl)amino)-7-(((3S)-tetrahydro-3-furanyl)oxy)-6-quinazolinyl)-4-(dimethylamino)-, (2E)-
Public MeSH Note
2019; AFATINIB was indexed under QUINAZOLINES 2007-2018
History Note
2019 (2007)
Date Established
2019/01/01
Date of Entry
2018/07/09
Revision Date
2018/07/03
Afatinib Preferred
BIBW-2992-MA2 Narrower
Afatinib Maleate Narrower
BIBW 2992 Narrower
Gilotrif Narrower
Afatinib Dimaleate Narrower
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