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Mast Cell Activation Disorders MeSH Descriptor Data 2022


MeSH Heading
Mast Cell Activation Disorders
Tree Number(s)
C20.762
Unique ID
D000090362
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000090362
Scope Note
A spectrum of primary, secondary, and idiopathic disorders involving MAST CELLS and characterized by an aberrant release of mast cell mediators which result in multiple and variable inflammatory and allergic symptoms. These disorders are associated with various mutations in tyrosine kinase KIT (PROTO-ONCOGENE PROTEINS C-KIT) and other genes, underlying conditions, and responses to allergic or non-allergic triggers of mast cell stimulation and degranulation such as local anesthetics, lactam antibiotics, muscle relaxants, specific foods, environmental toxins, physical conditions such as vibration, cold, pressure, and stress.
Entry Term(s)
Clonal Mast Cell Proliferation Disorders
Mast Cell Activation Disease
Mast Cell Disease
Mast-Cell Disease
Monoclonal Mast Cell Activation Syndrome
Primary Mast Cell Activation Disorders
Public MeSH Note
2022; for MAST CELL ACTIVATION DISEASE see MASTOCYTOSIS 2018-2021
History Note
2022; for MAST CELL ACTIVATION DISEASE use MASTOCYTOSIS 2018-2021
Date Established
2022/01/01
Date of Entry
2021/07/09
Revision Date
2021/07/07
Mast Cell Activation Disorders Preferred
Primary Mast Cell Activation Disorders Narrower
Monoclonal Mast Cell Activation Syndrome Narrower
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