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Medium Spiny Neurons MeSH Descriptor Data 2023


MeSH Heading
Medium Spiny Neurons
Tree Number(s)
A08.675.289.500
A08.675.650.535
A11.671.285.500
A11.671.650.535
Unique ID
D000094242
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000094242
Scope Note
Medium sized, inhibitory GABAergic neurons in the CORPUS STRIATUM with highly developed dendritic trees. They are divided into neurons expressing DOPAMINE D1 RECEPTORS which project preferentially to the SUBSTANTIA NIGRA PARS RETICULATA and neurons expressing DOPAMINE D2 RECEPTORS which project preferentially to the lateral part of the GLOBUS PALLIDUS. Medium spiny neurons are preferentially lost in HUNTINGTON DISEASE.
Entry Term(s)
Striatal Medium-Sized Spiny Neurons
Previous Indexing
Corpus Striatum (1983-2022)
Neurons (1983-2022)
See Also
Corpus Striatum
Public MeSH Note
2023
History Note
2023
Date Established
2023/01/01
Date of Entry
2022/07/12
Revision Date
2022/07/12
Medium Spiny Neurons Preferred
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