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Immune System Exhaustion
MeSH Descriptor Data 2024
Details
Qualifiers
MeSH Tree Structures
Concepts
MeSH Heading
Immune System Exhaustion
Tree Number(s)
G12.590
Unique ID
D000095842
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000095842
Scope Note
A spectrum of functional deterioration in various lymphocyte populations that is induced by continuous antigenic stimulation. There are overlapping similarities with
CELLULAR SENESCENCE
;
IMMUNOSENESCENCE
;
T-CELL SENESCENCE
; and
CLONAL ANERGY
.
Entry Term(s)
B-Cell Exhaustion
Immune Exhaustion
Lymphocyte Exhaustion
Monocyte Exhaustion
NK Cell Exhaustion
Poly-Lymphocyte Exhaustion
Public MeSH Note
2024
History Note
2024
Date Established
2024/01/01
Date of Entry
2023/07/26
Revision Date
2022/11/17
Allowable Qualifiers
drug effects (DE)
genetics (GE)
immunology (IM)
physiology (PH)
radiation effects (RE)
Immune System Phenomena [G12]
Antibody Affinity [G12.040]
Antibody Specificity [G12.100]
Antibody-Dependent Enhancement [G12.113]
Antigen Presentation [G12.119]
Antigen-Antibody Reactions [G12.122]
Binding Sites, Antibody [G12.125]
Blood Group Incompatibility [G12.186]
CD4-CD8 Ratio [G12.248]
Clonal Selection, Antigen-Mediated [G12.261]
Complement Activation [G12.274]
Cytotoxicity, Immunologic [G12.287]
Dose-Response Relationship, Immunologic [G12.300]
Histamine Release [G12.350]
HIV Seronegativity [G12.400]
Immune Evasion [G12.413]
Immune Reconstitution [G12.432]
Immunity [G12.450]
Immunocompetence [G12.460]
Immunocompromised Host [G12.470]
Immunogenetic Phenomena [G12.500]
Immunogenicity, Vaccine [G12.513]
Immunologic Surveillance [G12.525]
Immunomodulation [G12.535]
Lymphocyte Activation [G12.565]
Lymphocyte Cooperation [G12.575]
Immune System Exhaustion [G12.590]
T-Cell Exhaustion [G12.590.500]
Neutrophil Activation [G12.604]
Neutrophil Infiltration [G12.632]
Phagocytosis [G12.688]
Seroconversion [G12.800]
Th1-Th2 Balance [G12.838]
Transplantation Immunology [G12.875]
Trogocytosis [G12.888]
Tumor Escape [G12.900]
Expand All
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Immune System Exhaustion
Preferred
Concept UI
M000758902
Scope Note
A spectrum of functional deterioration in various lymphocyte populations that is induced by continuous antigenic stimulation. There are overlapping similarities with
CELLULAR SENESCENCE
;
IMMUNOSENESCENCE
;
T-CELL SENESCENCE
; and
CLONAL ANERGY
.
Terms
Immune System Exhaustion
Preferred Term
Term UI
T001125301
Date
10/07/2022
LexicalTag
NON
ThesaurusID
NLM (2024)
Immune Exhaustion
Term UI
T001125809
Date
10/19/2022
LexicalTag
NON
ThesaurusID
NLM (2024)
Poly-Lymphocyte Exhaustion
Narrower
Concept UI
M000758903
Scope Note
Concurrent multiple types of lymphocyte exhaustion.
Terms
Poly-Lymphocyte Exhaustion
Preferred Term
Term UI
T001125298
Date
10/07/2022
LexicalTag
NON
ThesaurusID
NLM (2024)
NK Cell Exhaustion
Narrower
Concept UI
M000758904
Terms
NK Cell Exhaustion
Preferred Term
Term UI
T001125299
Date
10/07/2022
LexicalTag
NON
ThesaurusID
NLM (2024)
B-Cell Exhaustion
Narrower
Concept UI
M000758905
Terms
B-Cell Exhaustion
Preferred Term
Term UI
T001125300
Date
10/07/2022
LexicalTag
NON
ThesaurusID
NLM (2024)
Monocyte Exhaustion
Related
Concept UI
M000758906
Terms
Monocyte Exhaustion
Preferred Term
Term UI
T001125302
Date
10/07/2022
LexicalTag
NON
ThesaurusID
NLM (2024)
Lymphocyte Exhaustion
Narrower
Concept UI
M000759152
Terms
Lymphocyte Exhaustion
Preferred Term
Term UI
T001125297
Date
10/07/2022
LexicalTag
NON
ThesaurusID
NLM (2024)
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