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Antibody Affinity MeSH Descriptor Data 2022


MeSH Heading
Antibody Affinity
Tree Number(s)
G12.040
G12.122.125
Unique ID
D000915
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000915
Annotation
do not confuse with BINDING SITES, ANTIBODY or ANTIGENIC DETERMINANTS
Scope Note
A measure of the binding strength between antibody and a simple hapten or antigen determinant. It depends on the closeness of stereochemical fit between antibody combining sites and antigen determinants, on the size of the area of contact between them, and on the distribution of charged and hydrophobic groups. It includes the concept of "avidity," which refers to the strength of the antigen-antibody bond after formation of reversible complexes.
Entry Term(s)
Affinity, Antibody
Antibody Avidity
Avidity, Antibody
NLM Classification #
QW 570
Previous Indexing
Antibodies (1966-1978)
Antigen-Antibody Reactions (1966-1978)
Antigenic Determinants (1970-1978)
Binding Sites, Antibody (1973-1978)
Public MeSH Note
79
History Note
79
Date Established
1979/01/01
Date of Entry
1977/12/02
Revision Date
2016/06/02
Antibody Affinity Preferred
Antibody Avidity Narrower
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