NLM Logo

Lymphocyte Activation MeSH Descriptor Data 2022


MeSH Heading
Lymphocyte Activation
Tree Number(s)
E01.370.225.812.482
E05.200.812.482
E05.478.594.530
G12.450.050.400.545
G12.565
Unique ID
D008213
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D008213
Annotation
lymphocyte transformation test goes here but do not index under specific agent inducing transformation unless particularly discussed; do not use for neoplastic transformation of lymphocytes ( = CELL TRANSFORMATION, NEOPLASTIC) or viral transformation of lymphocytes ( = CELL TRANSFORMATION, VIRAL); blast transformation in chronic myelogenous leukemia does not go here: index BLAST CRISIS
Scope Note
Morphologic alteration of small B LYMPHOCYTES or T LYMPHOCYTES in culture into large blast-like cells able to synthesize DNA and RNA and to divide mitotically. It is induced by INTERLEUKINS; MITOGENS such as PHYTOHEMAGGLUTININS, and by specific ANTIGENS. It may also occur in vivo as in GRAFT REJECTION.
Entry Term(s)
Blast Transformation
Blastogenesis
Lymphoblast Transformation
Lymphocyte Stimulation
Lymphocyte Transformation
Transformation, Blast
Transformation, Lymphoblast
Transformation, Lymphocyte
Previous Indexing
Lymphocytes/immunology (1966-1968)
See Also
Blast Crisis
Public MeSH Note
2003; see LYMPHOCYTE TRANSFORMATION 1972-2002; for BLAST TRANSFORMATION see BLAST CRISIS 1987-1992
History Note
2003 (1969); for BLAST TRANSFORMATION use BLAST CRISIS 1987-1992
Date Established
1972/01/01
Date of Entry
1999/01/01
Revision Date
2019/05/24
Lymphocyte Activation Preferred
page delivered in 0.16s