MeSH Browser

MeSH Heading: Gap Junction beta-1 Protein
Tree Number(s): D12.776.543.585.250.600
Unique ID: D000097002
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000097002
Scope Note: A GAP JUNCTION beta subunit containing four transmembrane domains expressed in myelinating SCHWANN CELLS and is localized to peripheral MYELIN (e.g., noncompact myelin in the paranode and Schmitt-Lanterman incisures). Mutations in the human gene GJB1 are associated with X-linked CHARCOT-MARIE-TOOTH DISEASE type 1 (CMT1X).
Entry Term(s): Connexin 32; Connexin 32 Protein; Cx32 Protein; GJB1 Protein; Gap Junction B1; Gap Junction beta1 Protein
Public MeSH Note: 2024; see under CONNEXINS 1993-2023
History Note: 2024(1993)
Date Established: 2024/01/01
Date of Entry: 2023/07/26
Revision Date: 2023/05/31

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M000762845
Scope Note: A GAP JUNCTION beta subunit containing four transmembrane domains expressed in myelinating SCHWANN CELLS and is localized to peripheral MYELIN (e.g., noncompact myelin in the paranode and Schmitt-Lanterman incisures). Mutations in the human gene GJB1 are associated with X-linked CHARCOT-MARIE-TOOTH DISEASE type 1 (CMT1X).
Terms: Gap Junction beta-1 Protein Preferred Term
Term UI T001135651
Date03/30/2023
LexicalTag NON
ThesaurusID NLM (2024); Gap Junction B1
Term UI T001133105
Date02/22/2023
LexicalTag NON
ThesaurusID NLM (2024); Cx32 Protein
Term UI T001133106
Date02/22/2023
LexicalTag ABX
ThesaurusID NLM (2024); GJB1 Protein
Term UI T001133107
Date02/22/2023
LexicalTag ABX
ThesaurusID NLM (2024); Connexin 32 Protein
Term UI T001135653
Date03/30/2023
LexicalTag NON
ThesaurusID NLM (2024); Gap Junction beta1 Protein
Term UI T001135654
Date03/30/2023
LexicalTag NON
ThesaurusID NLM (2024); Connexin 32
Term UI T001135652
Date03/30/2023
LexicalTag NON
ThesaurusID NLM (2024)

Gap Junction beta-1 Protein MeSH Descriptor Data 2024