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Amoxapine MeSH Descriptor Data 2022


MeSH Heading
Amoxapine
Tree Number(s)
D03.633.300.347.500.040
Unique ID
D000657
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000657
Scope Note
The N-demethylated derivative of the antipsychotic agent LOXAPINE that works by blocking the reuptake of norepinephrine, serotonin, or both; it also blocks dopamine receptors. Amoxapine is used for the treatment of depression.
Entry Term(s)
2-Chloro-11-(1-piperazinyl)dibenz(b,f)(1,4)oxazepine
Asendin
Asendis
CL-67,772
Demolox
Desmethylloxapine
Défanyl
Pharm Action
Antidepressive Agents, Tricyclic
Neurotransmitter Uptake Inhibitors
Serotonin Uptake Inhibitors
Dopamine Antagonists
Adrenergic Uptake Inhibitors
Registry Number
R63VQ857OT
Related Numbers
14028-44-5
CAS Type 1 Name
Dibenz(b,f)(1,4)oxazepine, 2-chloro-11-(1-piperazinyl)-
Previous Indexing
Dibenzoxazepines (1971-1974)
Piperazines (1971-1974)
Public MeSH Note
91; was see under DIBENZOXAZEPINES 1975-90
History Note
91(75); was see under DIBENZOXAZEPINES 1975-90
Date Established
1991/01/01
Date of Entry
1974/11/27
Revision Date
2018/07/02
Amoxapine Preferred
CL-67,772 Narrower
Demolox Narrower
Asendin Narrower
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