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Neurotransmitter Uptake Inhibitors MeSH Descriptor Data 2022


MeSH Heading
Neurotransmitter Uptake Inhibitors
Tree Number(s)
D27.505.519.562.437
D27.505.519.625.600
D27.505.696.577.600
Unique ID
D014179
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D014179
Annotation
general or unspecified; prefer specific groups or specific drugs; coordinate with specific neurotransmitters /‌physiol
Scope Note
Drugs that inhibit the transport of neurotransmitters into axon terminals or into storage vesicles within terminals. For many transmitters, uptake determines the time course of transmitter action so inhibiting uptake prolongs the activity of the transmitter. Blocking uptake may also deplete available transmitter stores. Many clinically important drugs are uptake inhibitors although the indirect reactions of the brain rather than the acute block of uptake itself is often responsible for the therapeutic effects.
Entry Version
NEUROTRANSM UPTAKE INHIB
Entry Term(s)
Inhibitors, Neurotransmitter Uptake
Reuptake Inhibitors, Neurotransmitter
Transmitter Uptake Inhibitors, Neuronal
Uptake Inhibitors, Neurotransmitter
Registry Number
0
NLM Classification #
QV 126
Previous Indexing
Cytoplasmic Granules (1966-1977)
Kinetics (1966-1984)
Nerve Endings (1966-1973)
Synapses (1966-1971)
Synaptic Vesicles (1972-1973)
Synaptosomes (1974-1984)
Public MeSH Note
93; was TRANSMITTER UPTAKE INHIBITORS, NEURONAL 1985-92; NEUROTRANSMITTER UPTAKE INHIBITORS, INHIBITORS OF NEUROTRANSMITTER UPTAKE & UPTAKE INHIBITORS, NEUROTRANSMITTER were see TRANSMITTER UPTAKE INHIBITORS, NEURONAL 1985-92
Online Note
use NEUROTRANSMITTER UPTAKE INHIBITORS to search TRANSMITTER UPTAKE INHIBITORS, NEURONAL; INHIBITORS OF NEUROTRANSMITTER UPTAKE & UPTAKE INHIBITORS, NEUROTRANSMITTER 1985-92
History Note
93; WAS TRANSMITTER UPTAKE INHIBITORS, NEURONAL 1985-92; NEUROTRANSMITTER UPTAKE INHIBITORS, INHIBITORS OF NEUROTRANSMITTER UPTAKE & UPTAKE INHIBITORS, NEUROTRANSMITTER were see TRANSMITTER UPTAKE INHIBITORS, NEURONAL 1985-92
Date Established
1985/01/01
Date of Entry
1984/05/01
Revision Date
2019/05/24
Neurotransmitter Uptake Inhibitors Preferred
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