MeSH Browser

MeSH Heading: Bromodeoxyuridine
Tree Number(s): D03.383.742.680.852.300.150; D13.570.230.430.196; D13.570.685.852.300.150
Unique ID: D001973
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D001973
Scope Note: A nucleoside that substitutes for thymidine in DNA and thus acts as an antimetabolite. It causes breaks in chromosomes and has been proposed as an antiviral and antineoplastic agent. It has been given orphan drug status for use in the treatment of primary brain tumors.
Entry Term(s): 5-Bromo-2'-deoxyuridine; 5-Bromodeoxyuridine; BUdR; BrdU; Bromouracil Deoxyriboside; Broxuridine; NSC-38297
Pharm Action: Antimetabolites
Antimetabolites, Antineoplastic
Antiviral Agents
Radiation-Sensitizing Agents
Registry Number: G34N38R2N1
Related Numbers: 59-14-3
CAS Type 1 Name: Uridine, 5-bromo-2'-deoxy-
Public MeSH Note: 66
History Note: 66(65)
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/05/27

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0002951
Registry Number: G34N38R2N1
Related Numbers: 59-14-3
Scope Note: A nucleoside that substitutes for thymidine in DNA and thus acts as an antimetabolite. It causes breaks in chromosomes and has been proposed as an antiviral and antineoplastic agent. It has been given orphan drug status for use in the treatment of primary brain tumors.
Terms: Bromodeoxyuridine Preferred Term
Term UI T005621
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1965); Bromouracil Deoxyriboside
Term UI T005622
Date05/23/1980
LexicalTag NON
ThesaurusID UNK (19XX); 5-Bromo-2'-deoxyuridine
Term UI T005627
Date03/28/1996
LexicalTag NON
ThesaurusID; BrdU
Term UI T005625
Date03/08/1989
LexicalTag ABB
ThesaurusID NLM (1990); BUdR
Term UI T005626
Date03/29/1974
LexicalTag ABB
ThesaurusID; 5-Bromodeoxyuridine
Term UI T005620
Date10/26/1981
LexicalTag NON
ThesaurusID UNK (19XX); Broxuridine
Term UI T005623
Date05/23/1980
LexicalTag NON
ThesaurusID

Bromodeoxyuridine MeSH Descriptor Data 2024