MeSH Browser

MeSH Heading: Floxuridine
Tree Number(s): D03.383.742.680.852.300.350; D13.570.230.430.432; D13.570.685.852.300.350
Unique ID: D005467
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D005467
Annotation: an antiviral & antineoplastic antimetabolite
Scope Note: An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection; when administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
Entry Term(s): 5-FUdR; 5-Fluorodeoxyuridine; FUdR; Fluorodeoxyuridine
Pharm Action: Antimetabolites, Antineoplastic
Related Numbers: 50-91-9
CAS Type 1 Name: Uridine, 2'-deoxy-5-fluoro-
Public MeSH Note: 93; was FLUORODEOXYURIDINE 1963-92; FLOXURIDINE was see FLUORODEOXYURIDINE 1976-92
Online Note: use FLOXURIDINE to search FLUORODEOXYURIDINE 1966-92
History Note: 93; was FLUORODEOXYURIDINE 1963-92; FLOXURIDINE was see FLUORODEOXYURIDINE 1976-92
Date Established: 1993/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/05/31

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0008626
Related Numbers: 50-91-9
Scope Note: An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection; when administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
Terms: Floxuridine Preferred Term
Term UI T016633
Date01/01/1999
LexicalTag NON
ThesaurusID; 5-Fluorodeoxyuridine
Term UI T016631
Date10/23/1981
LexicalTag NON
ThesaurusID UNK (19XX); 5-FUdR
Term UI T016632
Date10/09/1986
LexicalTag ABB
ThesaurusID UNK (19XX); Fluorodeoxyuridine
Term UI T016634
Date02/27/1992
LexicalTag NON
ThesaurusID; FUdR
Term UI T016635
Date03/30/1974
LexicalTag ABB
ThesaurusID

Floxuridine MeSH Descriptor Data 2024