MeSH Browser

MeSH Heading: Bromouracil
Tree Number(s): D03.383.742.698.875.237
Unique ID: D001976
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D001976
Annotation: an antimetabolite
Scope Note: 5-Bromo-2,4(1H,3H)-pyrimidinedione. Brominated derivative of uracil that acts as an antimetabolite, substituting for thymine in DNA. It is used mainly as an experimental mutagen, but its deoxyriboside (BROMODEOXYURIDINE) is used to treat neoplasms.
Entry Term(s): 5-Bromouracil; Bromuracil
Pharm Action: Antimetabolites
Mutagens
Related Numbers: 51-20-7
CAS Type 1 Name: 2,4(1H,3H)-Pyrimidinedione, 5-bromo-
Previous Indexing: Uracil (1966-1970)
Public MeSH Note: 74
History Note: 74(71)
Date Established: 1974/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/05/27

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Bromouracil MeSH Descriptor Data 2024