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A form of undifferentiated malignant LYMPHOMA usually found in central Africa, but also reported in other parts of the world. It is commonly manifested as a large osteolytic lesion in the jaw or as an abdominal mass. B-cell antigens are expressed on the immature cells that make up the tumor in virtually all cases of Burkitt lymphoma. The Epstein-Barr virus (HERPESVIRUS 4, HUMAN) has been isolated from Burkitt lymphoma cases in Africa and it is implicated as the causative agent in these cases; however, most non-African cases are EBV-negative.
Entry Term(s)
African Lymphoma
Burkitt Cell Leukemia
Burkitt Leukemia
Burkitt Tumor
Burkitt's Leukemia
Burkitt's Lymphoma
Burkitt's Tumor
Leukemia, Lymphoblastic, Burkitt-Type
Leukemia, Lymphocytic, L3
Lymphocytic Leukemia, L3
Lymphoma, Burkitt
Public MeSH Note
1998; see BURKITT'S LYMPHOMA 1968-1997; for LEUKEMIA, B-CELL, ACUTE & BURKITT LEUKEMIA see LEUKEMIA, B-CELL, ACUTE 1989-2007; for BURKITT TUMOR see BURKITT'S TUMOR 1968-1997; for LYMPHOMA, BURKITT see LYMPHOMA, BURKITT'S 1968-1997
A form of undifferentiated malignant LYMPHOMA usually found in central Africa, but also reported in other parts of the world. It is commonly manifested as a large osteolytic lesion in the jaw or as an abdominal mass. B-cell antigens are expressed on the immature cells that make up the tumor in virtually all cases of Burkitt lymphoma. The Epstein-Barr virus (HERPESVIRUS 4, HUMAN) has been isolated from Burkitt lymphoma cases in Africa and it is implicated as the causative agent in these cases; however, most non-African cases are EBV-negative.