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Cantharidin MeSH Descriptor Data 2022


MeSH Heading
Cantharidin
Tree Number(s)
D03.633.100.127.125
Unique ID
D002193
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D002193
Scope Note
A toxic compound, isolated from the Spanish fly or blistering beetle (Lytta (Cantharis) vesicatoria) and other insects. It is a potent and specific inhibitor of protein phosphatases 1 (PP1) and 2A (PP2A). This compound can produce severe skin inflammation, and is extremely toxic if ingested orally.
Entry Term(s)
Cantharides
Cantharidine
Pharm Action
Enzyme Inhibitors
Irritants
Registry Number
IGL471WQ8P
Related Numbers
56-25-7
CAS Type 1 Name
4,7-Epoxyisobenzofuran-1,3-dione, hexahydro-3a,7a-dimethyl-, (3aalpha,4beta,7beta,7aalpha)-
Public MeSH Note
79; was CANTHARIDES 1963-78
Online Note
use CANTHARIDIN to search CANTHARIDES 1966-78
History Note
79; was CANTHARIDES 1963-78
Date Established
1979/01/01
Date of Entry
1999/01/01
Revision Date
2016/05/27
Cantharidin Preferred
Cantharides Related
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