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Captopril MeSH Descriptor Data 2022


MeSH Heading
Captopril
Tree Number(s)
D12.125.072.401.623.270
Unique ID
D002216
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D002216
Scope Note
A potent and specific inhibitor of PEPTIDYL-DIPEPTIDASE A. It blocks the conversion of ANGIOTENSIN I to ANGIOTENSIN II, a vasoconstrictor and important regulator of arterial blood pressure. Captopril acts to suppress the RENIN-ANGIOTENSIN SYSTEM and inhibits pressure responses to exogenous angiotensin.
Entry Term(s)
(S)-1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline
Capoten
Lopirin
SQ-14,225
SQ-14,534
SQ-14225
SQ-14534
Pharm Action
Angiotensin-Converting Enzyme Inhibitors
Antihypertensive Agents
Registry Number
9G64RSX1XD
Related Numbers
62571-86-2
63250-36-2
CAS Type 1 Name
L-Proline, 1-(3-mercapto-2-methyl-1-oxopropyl)-, (S)-
Previous Indexing
Kininase II/antagonists & inhibitors (1973-1979)
Peptide Peptidohydrolases (1966-1967) /antagonists & inhibitors (1968-1972)
Proline (1966-1974) /antagonists & inhibitors (1975-1979)
Public MeSH Note
86; was see under PROLINE 1980-85; SQ 14225 was see CAPTOPRIL 1980-93
Online Note
use CAPTOPRIL to search SQ 14225 1980-93
History Note
86(80); was see under PROLINE 1980-85; SQ 14225 was see CAPTOPRIL 1980-93
Date Established
1986/01/01
Date of Entry
1979/05/23
Revision Date
2013/07/08
Captopril Preferred
Lopirin Narrower
SQ-14,534 Related
Capoten Narrower
SQ-14,225 Narrower
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