Cardiac manifestation of gastrointestinal CARCINOID TUMOR that metastasizes to the liver. Substances secreted by the tumor cells, including SEROTONIN, promote fibrous plaque formation in ENDOCARDIUM and its underlying layers. These deposits cause distortion of the TRICUSPID VALVE and the PULMONARY VALVE eventually leading to STENOSIS and valve regurgitation.
Entry Version
CARCINOID HEART DIS
NLM Classification #
WG 210
Public MeSH Note
91; was see under MALIGNANT CARCINOID SYNDROME 1964-90
Online Note
search MALIGNANT CARCINOID SYNDROME 1966-74
History Note
91(75)(64-72); was see under MALIGNANT CARCINOID SYNDROME 1964-90 (Prov 1964-72)
Cardiac manifestation of gastrointestinal CARCINOID TUMOR that metastasizes to the liver. Substances secreted by the tumor cells, including SEROTONIN, promote fibrous plaque formation in ENDOCARDIUM and its underlying layers. These deposits cause distortion of the TRICUSPID VALVE and the PULMONARY VALVE eventually leading to STENOSIS and valve regurgitation.
