MeSH Browser

MeSH Heading: Dichlororibofuranosylbenzimidazole
Tree Number(s): D13.570.800.330
Unique ID: D004004
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D004004
Scope Note: An RNA polymerase II transcriptional inhibitor. This compound terminates transcription prematurely by selective inhibition of RNA synthesis. It is used in research to study underlying mechanisms of cellular regulation.
Entry Version: DCRFB
Entry Term(s): 5,6-Dichloro-1-beta-D-ribofuranosyl-1-H-benzimidazol; 5,6-Dichloro-1-beta-ribofuranosylbenzimidazole; DRB; Dichlorobenzimidazole Riboside
Pharm Action: Enzyme Inhibitors
Nucleic Acid Synthesis Inhibitors
Registry Number: 53-85-0
CAS Type 1 Name: 1H-Benzimidazole, 5,6-dichloro-1-beta-D-ribofuranosyl-
Previous Indexing: Benzimidazoles (1966-1978); Nucleosides (1966-1970); Ribonucleosides (1971-1978)
Public MeSH Note: 91; was see under RIBONUCLEOSIDES 1979-90
History Note: 91(79); was see under RIBONUCLEOSIDES 1979-90
Date Established: 1991/01/01
Date of Entry: 1978/03/08
Revision Date: 1998/06/10

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0006279
Registry Number: 53-85-0
Scope Note: An RNA polymerase II transcriptional inhibitor. This compound terminates transcription prematurely by selective inhibition of RNA synthesis. It is used in research to study underlying mechanisms of cellular regulation.
Terms: Dichlororibofuranosylbenzimidazole Preferred Term
Term UI T012150
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1979); Dichlorobenzimidazole Riboside
Term UI T012149
Date03/08/1978
LexicalTag NON
ThesaurusID UNK (19XX); 5,6-Dichloro-1-beta-D-ribofuranosyl-1-H-benzimidazol
Term UI T012152
Date02/17/1996
LexicalTag NON
ThesaurusID NLM (1997); DRB
Term UI T012151
Date01/30/1981
LexicalTag ABB
ThesaurusID UNK (19XX); 5,6-Dichloro-1-beta-ribofuranosylbenzimidazole
Term UI T012148
Date08/22/1984
LexicalTag NON
ThesaurusID UNK (19XX)

Dichlororibofuranosylbenzimidazole MeSH Descriptor Data 2024